PATENTS, PUBLICATIONS AND BOOK CHAPTERS

 

 

PATENTS

 

 

1.

Orthopedic Implant with Self-Reinforced Mantle, Patent # 5,507,814, Issued, April 16, 1996

2.

Methods of Making Self-Reinforced Compositions of Amorphous Thermoplastics, Patent #5,679,299, October 27, 1997

3.

Bone Cement and Method of Preparation, Patent # 5,902,839, May 11, 1999

4.

Surface modification of Metallic Stents to Inhibit Hyperplasia, patent disclosure, 2001

5.

Medical Devices with Surface Modification for Regulating Cell Growth on or near the surface, Feb 9, 2006, Application No. 11/198,090

6.

Appl. #11/673674 Method of preparing BioMedical Surfaces. An electrochemical method to prepare Ti-alloy surfaces for medic device applications Invention disclosure, 12/18/05 , Provisional Patent, Patent submitted, Feb. 2007, claims allowed July 2011.

7.

Novel Two Solution Bone Cement Formulations Patent Filed, June 2007

8.

Electrochemical Control of Biological Interactions at Metallic Biomaterial Surfaces - Patent Filed, July 2009

9.

Method for Preparing Biomedical Surfaces, Patent #8,876,910, Nov. 4, 2014.

10.

Electrochemical Coupling of Metallic Biomaterial Implants for Biological Effect, Patent # 9,039764, 5/26/2015

11.

Prevention of Fretting Crevice Corrosion of Modular Taper Interfaces in Orthopedic Implants with serial No. 61/72 2,459, filed on 11/5/12.

12.

Smart Medical Devices for Electrochemical Monitoring and Control of Medical Implants, provisional patent, 3/15/2013.

13.

Medical Devices with Surface Modification for Regulating Cell Growth on or near the surface, Feb 9, 2006, Application No. 11/198,090

14.

Test method for assessing Corrosion of Metallic Cardiovascular Devices

15.

Electrochemical Eradication of Microbes on Surfaces of Objects, US/PCT Application No. 14/540,213.

 

 

PUBLICATIONS
Original Scientific Peer Reviewed Papers

 

 

2015

131.

Mali S, Gilbert JL, “Correlating Fretting Corrosion and Micromotions in Modular Tapers: Test Method Development and Assessment”, ASTM Special Technical Publication 1591 on Implant Modularity, Eds. Greenwald, Kurtz, Lemons, Mihalko, ASTM International, W. Conshohocken, PA, 2015, in press.

130.

Gilbert JL, Sivan S, Mali S, “Corrosion of Modular Tapers in Total Joint Replacements: A Critical Assessment of Design, Materials, Surfaces Structure, Mechanics, Electrochemistry and Biology”, ASTM Special Technical Publication on Implant Modularity, STP 1591, Eds. Greenwald, Kurtz, Lemons, Mihalko, ASTM Int 2015, in press.

129.

Ouellette ES, Gilbert JL¸ “Production and Characterization of Melt-Spun Poly(Ether Ether Ketone) Fibers for Biomedical Applications”, Polymer, Feb. 2015, DOI: 10.1016/j.polymer.2015.02.015.

128.

Gilbert JL, Sivan S, Liu Y, Kocagoz S, Arnholt C, Kurt SM, “Direct In Vivo Inflammatory Cell

Induced Corrosion of CoCrMo Implant Surfaces”, J Biomed Mat Res A, (2015); 103(1): 211-223.

 

 

 

2014

127.

Porter DA, Urban RM, Jacobs JJ, Gilbert JL, Rodriguez JA, Cooper HJ, “Modern Tapers are More Flexible: A Mechanical Analysis of THA Trunnion Designs”, Clin Orthop and Rel Res, (2014) 472:3963-3970.

126.

Arnholt CM, MacDonald DW, Tohfafarosh M, Gilbert JL, Rimnac CM, Kurtz SM, “Mechanically Assisted Taper Corrosion in Modular TKA”, J. Arthroplasty, 2014, 29(9):205-208.

125.

Laurindo CAH, Torres RD, Mali SA, Gilbert JL, Soares P, “Incorporation of Ca and P on Anodized Titanium Surface: Effect of High Current Density”, Mat Sci and Eng, 2014;37:223-231.

124.

Rodrigues DC, Gilbert JL, Bader RA, Hasenwinkel JM, “PMMA Brush-Containing Two-Solution Bone Cement: Preparation, Characterization, and Influence of Composition on Cement Properties”, J. Mat Sci: Mat and Med, 2014: 25;79-89.

123.

Kocagoz S, Underwood RJ, Sivan S, Gilbert JL, MacDonald DW, Day JS, Kurtz SM, “Does Taper Angle Clearance Influence Fretting and Corrosion Damage at the Head-Stem Interface?”, Seminars in Arthroplasty, 2014 24(4): 246-254.

 

 

2013

122.

Sivan S, Kaul S, Gilbert JL, “The effect of cathodic electrochemical potential on cell viability: voltage threshold and time dependence”, J Biomed Mat Res, Part B, May, 2013, Vol 101, No 8: 1489-1497.

121.

Haeri M, Gilbert JL, “Voltage-controlled cellular behavior on polarized cpTi with varying surface oxide thickness”, Bioelectrochemistry, (2013); 94:53–60.

120.

Haeri M, Gilbert JL, “Study of cellular dynamics on polarized CoCrMo alloy using time-lapse live-cell imaging”, Acta Biomaterialia, April 2013, 9(11): 9220-9228.

119.

Swaminathan V, Gilbert JL, “Potential and frequency effects on fretting corrosion of Ti6Al4V and CoCrMo surfaces”, J Biomed Mat Res – Part A, (2013) 101A(9):2602-2612.

118.

Kurtz SM, Kocagoz SB, Hanzlik JA, Underwood RJ, Gilbert JL, MacDonald DW, Lee GC, Mont MA, Kraay MJ, Klein GR, Parvizi J, Rimnac C, “Do Ceramic Heads Reduce Taper Fretting in Hip Arthroplasty? A retrieval Study”, Clin Orthop and Rel Res (2013) 471:3270-3282.

117.

Higgs GB, Hanzlik JA, MacDonald DW, Gilbert JL, Rimnac CM, Kurtz SM “Is increased modularity associated with taper damage in metal-on-metal total hip arthroplasty devices?”, J. Arthroplasty, (2013) 29(8) Supp, 2-6.

116.

Higgs GB, Hanzlik JA, MacDonald DW, Kane WM, Day JS, Klein GR, Parvizi J, Mont MA, Kraay MJ, Martell JM, Gilbert JL, Rimnac CM, Kurtz SN, “Method of Characterizing Fretting and Corrosion at the Various Taper Connections of Retrieved Modular Components from Metal-on-Metal Total Hip Arthroplasty”, Amer Soc for Testing and Mat, ASTM, Spec Tech Pub 1560 Metal-on-Metal Total Hip Replacement Devices, Eds., Kurtz, S, Greenwald, A, Mihalko, W, Lemmons, J, 2013, pp .

 

 

2012

115.

Haeri, M, Wollert, T, Langford, GM, Gilbert, JL, Electrochemical Control of Cell Death: Reduction-Induced Intrinsic Apoptosis and Oxidation-Induced Necrosis on CoCrMo Alloy In-vitro to be submitted, Biomaterials.

114.

Niepa, THR, Gilbert, JL, Ren, D, Controlling Pseudomonas Aeruginosa Persistent Biomaterials Infections by Weal Electrochemical Currents and Synergistic Effects with Tobramycin, to be submitted.

113.

Swaminathan, V, Gilbert, JL, Fretting Corrosion of CoCrMo and Ti6Al4V Metallic Biomaterial Interfaces: Model, Method and Behavior, submitted to Biomaterials, March 2012

112.

Rodrigues, DC, Gilbert, JL, Bader, R, Hasenwinkel, JM, PMMA Brush-Containing Two Solution Bone Cement: Preparation, Characterization, an dInflue3nce of Composition on Cement Properties, submitted, J Biomed Mat Res-Part B, Part B.

111.

Rodrigues, DC, Gilbert, JL, Hasenwinkel, JM, Influence of the Addition of Cross-Linked PMMA Nanospheres and Microspheres on the Residual Monomer Concentration and Kinetics of Cure of Two-Solution Bone Cement, submitted, J Biomed Mat Res, Part B.

110.

Swaminathan, V, Zeng, H, Lawrynowicz, D, Zhang, Z, Gilbert, JL, Electrochemical investigation of chromium nanocarbide coated Ti-6Al-4V and Co-Cr-Mo alloy substrates, Electrochemica Acta, 2012: 59;387-397.

109.

Gilbert, JL, Mali, SA, Urban, RM, Silverton, CD, Jacobs, JJ, "In-Vivo Oxide-Induced Stress Corrosion Cracking of Ti-6Al-4V in a Neck-Stem Modular Taper: Emergent Behavior in a New Mechanism of In-Vivo Corrosion, J Biomed Mat Res Part B: Applied Biomat, 2012: 100B(2); 584-594.

2011

108.

Szkotak, R, Niepa, THP, Jawrani, N, Gilbert, JL, Jones, MB, Ren, D Differential Gene Expression to Investigate the Effects of Low-level Electrochemical Currents on Bacillus Subtilis, AMB Express, 2011, 1:39.

107.

Gilbert, JL, Mali, SA, Urban, RM, Silverton, CD, Jacobs, JJ, "In-Vivo Oxide-Induced Stress Corrosion Cracking of Ti-6Al-4V in a Neck-Stem Modular Taper: Emergent Behavior in a New Mechanism of In-Vivo Corrosion", accepted, J Biomed Mat Res Part B: Applied Biomat, June 2011.

106.

Rodrigues, DC, Gilbert, JL, Bader, R, Hasenwinkel, JM, Two-Solution Bone Cements Containing PMMA Brushes: Properties and Effects of Brush Addition on the physical and Mechanical Performance of the Cement, J. Biomed Mat Res-Part B: Applied Biomat. Submitted

105.

Rodrigues, DC, Gilbert, JL, Hasenwinkel, JM, Effect of the Addition of Cross-Linked PMMA Nanospheres and Microspheres on the Residual Monomer Concentration and Kinetics of Cure of Two-Solution Bone Cement, submitted, J Biomed Mat Res, Part B.

104.

Swaminathan, V, Zeng, H, Lawrynowicz, D, Zhang, Z, Gilbert, JL, Electrochemical Investigation of Chromium Oxide Coated Ti-6Al-4V and Co-Cr-Mo Alloy Substrates, J Biomed Mat Res (B), 6 June 2011. DOI: 10.1002/jbm.b.31861

103.

Haeri, M, Gilbert, JL, The Voltage-Dependent Electrochemical Impedance Spectroscopy of CoCrMo Medical Alloy Using Time-Domain Techniques: Generalized Cauchy-Lorentz, and KWW-Randles Functions Describing Non-Ideal Interfacial Behavior, Corrosion Science, Feb. 2011, 53(2), pp 582-588.

102.

Gilbert, JL, The Dangers of Adopting a Tissue-Engineering-Centric Agenda: A Presidents Perspective, J Biomed Mat Res, 2011, 96A(2): 273-274.

101.

Swaminathan, V, Zeng, H, Lawrynowicz, D, Zhang, Z, Gilbert, JL, Electrochemical Investigation of Chromium Oxide Coated Ti-6Al-4V and Co-Cr-Mo Alloy Substrates, J Biomed Mat Res (B), 2011: 98B(2); 369-378.

100.

Haeri, M, Gilbert, JL, The Voltage-Dependent Electrochemical Impedance Spectroscopy of CoCrMo Medical lloy Using Time-Domain Techniques: Generalized Cauchy-Lorentz, and KWW-Randles Functions Describing Non-Ideal Interfacial Behavior, Corrosion Science, Feb. 2011, 53(2), pp 582-588.

2010

99.

Gilbert, JL, Lam, B, The Effect of Surface Abrasion on the Polarization Behavior of Co-Cr, Ti-6Al-4V and 316L Stainless Steel in Phosphate Buffered Saline at pH 7 and 2, Proceedings of 2009 Conference on Materials and Processes for Medical Devices, Ed., Gilbert, JL, ASM International, 2010.

98.

Haeri, M, Gilbert, JL, Cellular Response to Anodic and Cathodic Surface Voltage, and Metal Ion Release in Polarized CoCr Biomedical Alloy, Proceedings of 2009 Conference on Materials and Processes for Medical Devices, Ed., Gilbert, JL, ASM International, 2010.

97.

Wernle, JD, Gilbert, JL, Microscale and Nanoscale Surface Strain Mapping of Single Asperity Wear in Ultra High Molecular Weight Polyethylene: Effects of Materials, Load, and Asperity Geometry, J Biomed Mat Res (A), 2010, June: 93A(4);1442-1453.

96.

Ehrensberger, MT, Gilbert, JL, The Effect of Static Applied Potential on the 24 hour Impedance Behavior of Commercially Pure Titanium in Simulated Biological Conditions, J Biomed Mat Res Part (B), 2010, April: 93B(1); 106-112.

95.

Ehrensberger, MT, Gilbert, JL, The Effect of Scanning Electrochemical Potential on the Short-Term Impedance of Commercially Pure Titanium in Simulated Biological Conditions, J Biomed Mat Res Part A, 2010, Sept: 94A(3); 781-789.

94.

Ehrensberger, M, Sivan, S, Gilbert, JL, Titanium is NOT The Most Biocompatible Metal Under Cathodic Potentials: The Relationship Between Voltage and MC3T3 Pre-Osteoblast Behavior on Electrically Polarized cpTi Surfaces, J Biomed Mat Res Part (A), 2010, June: 93A(4); 1500-1509.

93.

Rodrigues, Gilbert, JL, Hasenwinkel, JM, Two-solution Bone Cements with Cross-Linked Micro- and Nano-particles for Vertebral Fracture Applications: Effects of Zircomium Dioxide Content on the Material and Setting Properties, J Biomed Mat Res (B), 2010, Jan: 92B(1); 12-23.

92.

Ehrensberger, MT, Gilbert, JL, A Time-Based Potential Step Analysis of Electrochemical Impedance Incorporating a Constant Phase Element: Study of Commercially Pure Titanium in Phosphate Buffered Saline, J. Biomed Mat Res (A), 2010, May: 93A(2); 576-584.

 

 

INVITED BOOK CHAPTERS, EDITED BOOKS, CONTRIBUTED ARTICLES

 

 

1.

Jacobs, JJ, Gilbert, JL, Urban, RM, "Corrosion of Metallic Implants", Advances in Total Joint Arthroplasty, ED. RM Stauffer et al, Mosby, 1994; 279-319.

2.

Gilbert, JL, "Basic Science: Metals", The Adult Hip, Raven Press, Ed. Callaghan, Rubash and Rosenberg, Lippencott-Raven Press, Vol. 1, 1997.

3.

Gilbert, JL, Acrylics in Biomedical Engineering, Chapter 38, Encyclopedia of Materials Science and Technology, 2001.

4.

Gilbert, JL, Mechanically Assisted Corrosion of Metallic Biomaterials, ASM International Handbook, Volume 13C: Corrosion, 826-836, 2006.

5.

Bai, Z, Gilbert, JL, Corrosion Performance of Stainless Steels, Cobalt, and Titanium Alloys in Biomedical Applications, ASM International, Vol. 13C Corrosion: Materials, Environments, and Industries, pp 837-852, 2006.

6.

Gilbert, JL, "Basic Science: Metals", The Adult Hip, 2nd Edition, Raven Press, Ed. Callaghan, Rubash and Rosenberg, Lippencott-Raven Press, Vol., Chapt. 8, 2006.

7.

Medical Device Materials IV, Proceedings of the Materials and Processes for Medical Devices Conference, Gilbert, JL, Editor, ASM International, 2008.

8.

Gilbert, JL, Orthopedic Implants: Current Issues, Medical Device Developments, Vol. 6, 2008.

9.

Gilbert, JL, Wernle, JD, Micro- and Nano-Indentation Testing of UHMWPE, Handbook of UHMWPE for Orthopedics, 2nd Edition, S Kurtz, Editor, Chapt. 33, Academic Press, NY, 2009, pp 497-508.

10.

Gilbert, JL, Electrochemical Behaviour of Metals in the Biological Milieu, Chapter 13, Comprehensive Biomaterials, Ed. Healy, Ducheyne, Kirkpatrick, Elsevier Press, 2011.

11.

Medical Device Materials V, Proceedings of the Materials and Processes for Medical Devices Conference, Gilbert, JL, Editor, ASM International, 2010.

12.

Gilbert, JL, Medical Implant Corrosion: Electrochemistry at Metallic Biomaterial Surfaces, Singer Press, 2012.

13.

Gilbert JL, "Basic Science: Metals", The Adult Hip, 3rd Edition, Raven Press, Ed. Callaghan, Rubash and Rosenberg, Lippencott-Raven Press, Vol. 1, Chapt. 8, 2015.

14.

Gilbert JL, Sivan S, Mali SA, Kim J, Karker M, Kubacki GW, “Methods of Retrieval Analysis of Metallic Implants”, Implant Retrieval Analysis in Orthopedic Surgery, Ed. Kurtz, SM, Mihalko, WM, Springer, In review, 2015.

15.

Gilbert JL, Kubacki GW, “Oxidative Stress, Inflammation and the Corrosion of Metallic Biomaterials: Corrosion Causes Biology and Biology Causes Corrosion”, Oxidative Stress and Biomaterials, Ed. TD Dziubla, DA Butterfield, Elsevier Press, in press, 2015, Chapt. 3.

 

 

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Prof. Jeremy Gilbert|303C Bowne Hall, Syracuse University,Syracuse, NY-13244| Phone no: 315.443.5555|Email:gilbert@syr.edu

Syracuse University | Department of Biomedical and Chemical Engineering | Syracuse Biomaterials Institute